On 1 March a two year programme began in the United Kingdom of phased transfer of all diabetics requiring insulin to insulin in a strength of 100 units/ml. Factors affecting the absorption of insulin from subcutaneous tissues include site of injection,' exercise,2 dose,3 strength of the insulin, volume, and the patient's age.4 We examined the effect of giving identical doses of soluble insulin in strengths of U-40 (40 units/ml) and U-100 (100 units/ml).
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