Wound healing is a complicated process in which the skin or the afflicted organ heals itself after an injury. In numerous animal models, scientific validation for the use of most of these botanical parts and species in the management and treatment of prenatal and postnatal complications has been reported. As a result of its bioactivity, biocompatibility, osteoconductivity, structural and chemical similarity to bone and teeth, host tissue bonding ability, and absence of inflammatory characteristic, it has the capacity to regenerate tissue. Our study aimed to identify the wound healing property of Tridax procumbens in Clinical models. In this study we have identified the various phytochemical activities such as cytotoxic effect, anti inflammatory, anti microbial, free radical scavenging and wound healing activity of tridax procumbens. It was found that Tridax procumbens accelerated the healing process by enhancing the epithelial regeneration of wounds. The potent activity of the herbal formulation can be attributed to the phyto-constituents present in the formulation enhance the wound healing effect. Additional research is necessary to understand both the target-based mechanism of action and other pharmacological effects