A prospective, comparative study to evaluate the efficacy of topical flurbiprofen in maintaining intraoperative mydriasis during cataract surgery was conducted. A total of 70 patients, undergoing small incision cataract surgery (SICS) with IOL insertion were randomized into either of the two treatment groups. Pre-operatively patients of both the group had pupillary dilatation with topical application of cyclopentolate eye drops. In addition, flurbiprofen group received 0.03% Flurbiprofen eye drops thirty minutes apart starting two hours before surgery. Intra operative mydriasis was measured at different stages of surgery such as Stage Ibefore anterior chamber entry, Stage II -Between anterior chamber entry, anterior capsulotomy, and nucleus delivery, Stage III-Nucleus delivery to complete cortex wash. The mean pupillary diameter at baseline was equal in both control (7.57 ±0.73) mm and (7.57 ±0.74) mm in Flurbiprofen groups. Standard error of mean of maintained intraoperative mydriasis in control vs. flurbiprofen group were: Stage I 7.08 ± 0.50mm vs. 7.00 ± 0.93, Stage II-5.37 ± 1.47mm vs. 5.74 ± 0.91mm and Stage III-4.28 ± 1.27mm vs. 4.00 ± 1.30mm which were not significant statistically. This study indicates that topical Flurbiprofen is not significantly effective in maintaining pupillary dilatation during SICS, compared to control group.

Poisoning is a major problem all over the world and comprises a significant bulk of hospital admissions at a tertiary care hospital. There has also been a change in the pattern of poisoning in various areas, hence, important to know the pattern of poisoning in a given region so as to enable in making a rapid clinical diagnosis, initiate proper treatment to reduce morbidity and mortality. To find out the patient profile, the common poisons and outcome of poisoning cases a retrospective analysis of all acute poisoning cases admitted to the casualty of M S. Ramaiah Medical College & Teaching Hospital for a period of one year was done. Data on age, sex, type of poisoning, poisonous substances consumed, treatment, outcome and counselling were analysed. The age varied from 1-80 years. The male female ratio was 1.05: 1. Majority of the poisoning cases were of 21-30 years. Moreover, 85% cases reported were intentional poisoning and 25% cases of poisoning were with miscellaneous agents followed by 22% each of organophosphorus & single medicinal preparations. During the hospital stay 87% of patients were discharged after effective treatment. Suicide attempts were common among adolescents and 69% of the cases were counseled.