Deuteriation in the side-chain of the long-chain alkylbenzenes using a homogeneous platinum(I1) catalyst occurs predominantly at the ccand terminal carbon positions, isotope incorporation progressively decreasing from n-butyl-to n-nonyl-benzenes; in the side-chain of 1,l-dimethylpropylbenzene exchange is exclusively a t the y-position. THE deuteriation of methane and ethane has been reported,l employing a homogeneous platinum(I1) catalyst previously discovered for aromatic compounds.2 The work has been

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Novel methods have been developed for the preparation of polymers suitable for the attachment of enzymes, or other biochemical macromolecules, to render them water insoluble. By a new irradiation process, p‐nitrostyrene has been graft copolymerized to trunk polymers, such as polypropylene. Reduction of the nitro group in the graft copolymer gives the amino derivative, which may be converted to other functional groups (isothiocyanato or diazo) or used in conjunction with bifunctional reagents in order to covalently bind enzymes to produce active, water‐insoluble conjugates. The properties of one such conjugate, in which trypsin was immobilized by covalent attachment to poly(p‐isothiocyanatostyrene‐g‐propylene) are discussed. The advantages of the present radiation grafting technique are compared with conventional methods for insolubilizing enzymes.

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