Thrombosis of the venous system in the brain is a cause of cerebral infarction, second only to arterial disease, but is associated with high levels of morbidity and mortality. The clinical picture of cerebral venous thrombosis is highly variable and often presents a source of confusion to physicians. This study aimed to establish the clinical picture of cerebral venous thrombosis in patients in a tertiary healthcare center. We collected and analysed the case records of 23 patients with CVT. The most predominant presenting complaint was headache (47.8%) followed by vomiting (26%). The most common site of involvement was found to be the superior sagittal sinus (34.8%). Multiple sites of involvement were more common than a single site.

The thalamus is a walnut-sized structure that is located in the brain which receives rich blood supply from posterior cerebral artery and its communicating branches. One of the unusual presentations is the infarction of artery of percheron. Hereby reporting a case of 68-year-old female with no known co-morbidities who presented to the emergency department with complaints of sudden onset loss of consciousness in the morning. On further investigation, was found to have infarction of one of the variants of thalamic perforating arteries.

Primary hypothyroidism is a common endocrine condition that is encountered. Graves disease and Hashimoto’s thyroiditis are the most common autoimmune conditions in which conversion of hyperthyroidism to hypothyroidism is seen. Chances of conversion of hypothyroidism to hyperthyroidism is extremely rare. This case highlights that there should be a high index of suspicion for a possible conversion of hypothyroidism to hyperthyroidism. The etiology being an autoimmune switch by an external stimulus in genetically susceptible individuals. Hereby, presenting a case of 53-years female, who is a known case of type II diabetes mellitus, chronic kidney disease, nephrotic syndrome diagnosed with minimal change disease who presented with a hormonal profile showing hyperthyroidism. She had a history of hypothyroidism in the past for 12-years and was treated with levothyroxine and was off treatment for the past 2 years. Further evaluation showed presence of primary Sjogren’s syndrome which has let to this conversion.