Unmanned aerial vehicles (UAVs) play an increasingly important role in various areas of life, including in terms of protection and security. As a result of fires, volcanic eruptions, or other emergencies, huge amounts of toxic gases, dust, and other substances are emitted into the environment, which, together with high temperature, often leads to serious environmental contamination. Based on the available literature and patent databases, an analysis of the available UAVs models was carried out in terms of their applicability in air contaminated conditions in industrial areas, in the event of emergencies, such as fire, chemical contamination. The possibilities of using the devices were analyzed in terms of weather conditions, construction, and used materials in CBRN (chemical, biological, radiological, nuclear) threat situations. It was found that, thanks to the use of appropriate sensors, cameras, and software of UAVs integrated with a given system, it is possible to obtain information on air quality at a given moment, which is very important for the safety of people and the environment. However, several elements, including the possibility of use in acidification conditions, requires refinement to changing crisis conditions.