Two-stage hepatectomy provides a 5-year survival of 42% and a hope of long-term survival for selected patients with extensive bilobar CLM, irresectable by any other means.

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This study provides detailed data on the current characteristics, perceptions and outcomes of 45 young people with cystic fi brosis (CF) as they transition into adulthood. Although many had severe disease, they generally coped well, found attendance at a transition clinic helpful and welcomed the increased independence of an adult healthcare environment. Levels of psychological distress were low with only 15.6% having anxiety and 6.7% depression. The main psychological coping strategy used was optimistic acceptance. Overall, most remained stable after transfer but 33% had some decline in lung function and 9% in nutritional status, requiring intensification of treatment. They had high levels of satisfaction with their relationships and life situations and 76% were in employment or education. These results are encouraging and as life expectancy improves, young adults with CF are coping well with transition into adulthood.

Multiple subcutaneous swellings and discharging sinuses were a result of steatitis in three dogs. The steatitis in each case was thought to be associated with a pancreatic carcinoma. The association with pancreatic neoplasia had been suspected in life in only one dog but was confirmed at necropsy in each case. Circulating levels of pancreatic enzymes were increased in the one dog in which they were measured.