The maxillary sinus or antrum is the largest of the paranasal sinuses. It is located in the maxillary bone and has a proximity to the apexes of upper molars and premolars, which allows it to form a direct link between the sinus and the oral cavity. Dislocation of a foreign body or tooth to the interior of a paranasal sinus is a situation that can occur as a result of car accidents, firearm attacks, or iatrogenic in surgical procedures. Therefore, it is necessary to know how to treat this kind of situation. This study's objective is to report the case of a 23-year-old female patient, leucoderma, who sought treatment from the Surgical Unit at the Dental Faculty of the Federal University of Sergipe. She had a history of pain and edema in the right side of the genian region and two failed attempts at removing dental unit (DU) 18. The extraoral clinical exam revealed intense edema of the left hemiface with signs of infection, excoriation of the labial commissure, hematoma, a body temperature of 39°C, and a limited ability to open her mouth. The patient was medicated and treated surgically. The tooth was removed from the maxillary sinus with caution, as should have been done initially.
The anti-nociceptive and antioxidant activities of the Anadenantheracolubrina stem bark aqueous extract (AEAC) were investigated. AEAC (30 μg/mL) reduced 94.8% of 2,2-diphenyl-1-picrylhydrazyl radical and prevented 64% (200 μg/mL) of lipid peroxidation caused by 2,2'-azobis(2-methylpropionamidine) dihydrochloride-induced peroxyl radicals. AEAC treatment (200 and 400 mg/kg) significantly (p < 0.001) reduced mice orofacial nociception in the first (61.4% and 62.6%, respectively) and second (48.9% and 61.9%, respectively) phases of the formalin test. Nociception caused by glutamate was significantly (p < 0.001) reduced by up to 79% at 400 mg/kg, while 56-60% of the nociceptive behaviour induced by capsaicin was significantly inhibited by AEAC (100-400 mg/kg). Mice treated with AEAC did not show changes in motor performance in the Rota-rod apparatus. It appears that AEAC is of pharmacological importance in treating pain due to its anti-nociceptive effects, which were shown to be mediated by central and peripheral mechanisms.
Objetivo: comparar cobertura vacinal nos Estados brasileiros por Influenza Vírus no período de 2019 a 2020.
Metodologia: estudo observacional em que foram utilizados dados do DATASUS. Realizadas análises de séries temporais para a cobertura vacinal no período de 2000 a 2019. Foram ainda realizados teste t de Student comparando a cobertura vacinal contra o Influenza vírus nos anos de 2019 e 2020.
Resultados: foram verificadas as variações percentuais anuais (VPA) nos Estados brasileiros dos anos de 2000 a 2019, sendo verificado um percentual estacionário em relação a cobertura vacinal na maioria dos Estados. Em relação a cobertura vacinal contra o Influenza vírus, no período de 2019 e 2020 (campanhas vacinais), verifica-se diferença estatisticamente significativa para os grupos avaliados, exceto indígenas (p=0,97) e total (p=0,19), teste t de Student.
Conclusão: A pandemia do COVID 19 prejudicou grupos populacionais quanto a vacinação contra o Influenza vírus, como gestantes, crianças e puérperas.
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