Objective: The current study was aimed to evaluate and assess the correlation between adulterations of haematological parameters with high level of triglyceride in healthy smoker individuals. Methods: Ninety volunteers were participated in this study, smokers (n=70) and non-smokers (n=20). Complete blood count and other tests were performed by using fully automated haematological analyser devices. Results: The values of white blood cells (p=0.005), red blood cells (p= 0.01), haemoglobin content (p=0.03), haematocrit (p= 0.042), mean corpuscular haemoglobin and mean corpuscular volume (p= 0.003 and p= 0.0022 respectively) in smokers showed greater when compared to no-smokers. The values of total cholesterol and triglyceride appeared significantly greater in smokers than in control subjects. All other calculated measure parameters did not show significantly different between the two groups. Conclusions: The current study showed that continues cigarette smoking among healthy individuals has adverse effects on both biochemical and haematological parameters but not in kidney function activities. There is a strong correlation between high levels of triglyceride with increased levels of blood parameters in smoker group.