Observations of students of the Information Technology Education Study Program found problems in learning, namely the unavailability of innovative and integrated modules with technology. Alternative media used in learning activities in the form of print modules that are no longer suitable for use, the content of the material in the module is not updated. Then there is campus e-learning that cannot be used, due to limited learning features. Based on these problems, this study aims to develop a mobile web-based flash flipbook e-module in the database system course. This study uses Research and Development (R&D) research methods, the development model used is a 4D model consisting of four stages, namely defining, designing, developing, and distributing. This media is designed using the Flipbookmaker application and the HTML, PHP and JavaScript programming languages. The results of this study are: (1) the validity is declared valid on aspects of software, learning media and material content with an average of 0.91 valid categories; (2) practicality is determined by the responses of lecturers and students with an average of 88.92% in the valid category and student responses with an average of 87.44% in the practical category. (3) the effectiveness is declared effective based on the learning outcomes test obtained classically by 85% of students have passed, the paired t test shows a significant difference level of 0.028 > 0.05. Thus, the web-based mobile web-based flash flipbook e-learning module is effectively used as a learning medium.