We show that we have developed a reliable method to isolate miRNAs from small volumes of saliva, and that the saliva-derived miRNAs miR-9, miR-134 and miR-191 may serve as novel biomarkers to reliably detect HNSCC.

This review gives an overview on the miRNAs regulating the development of head and neck cancers. The ultimate establishment of miRNA expression profiles that are HNSCC specific, and miRNAs that orchestrate altered gene and protein expression levels in HNSCC, could pave the way for a better understanding of the mechanism underlying its pathogenesis and the development of novel, targeted therapies.

No abstract

Dermoid cyst of the floor of the mouth is a rare condition. It usually present as a non‐tender, slow growing swelling at the sublingual region. The clinical presentation may be similar to several other conditions. We report a case of an adolescent female who present at our institution with a sublingual swelling which was initially diagnosed as a plunging ranula. The lesion was excised together with the sublingual gland and then diagnosed histologically as a dermoid cyst. Post‐operative healing was uneventful. This report will also review the current literature on the clinical, radiological and histological aspect of the dermoid cyst to give the reader a greater understanding of this rare condition.

No abstract