No abstract

Glomerulosclerosis was found in 47% of 64 nonobese genetically "diabetic" KK mice. The changes consisted of a progressive increase in mesangial matrix and cells forming diffuse lesions. Nodular-type lesions,

Various fractions of sodium hyaluronate were injected into the suprachoroidal space of rabbit eyes via the pars plana as ‘internal’ buckles. The areas of elevated choroid were diffuse, usually extending over approximately one quadrant. The buckling effect was short-lived, in the range of 12–72 h, but sodium hyaluronate actually survived in the suprachoroidal space up to 10–14 days or more. No significant differences between buckles created by sodium hyaluronate 1 and 2%, or by cross-linked sodium hyaluronate were observed. Internal buckling of the choroid may prove to be a viable adjunct or alternative to conventional buckling procedures in the future.

No abstract

Four perfluorocarbon gases were injected into the suprachoroidal space of rabbit eyes. Temporary, expanding choroidal detachments were observed in all cases. Depending on the amount of gas injected (0.1 or 0.2 cc, respectively), they lasted 1 or 2 days in the case of perfluoromethane, 4 or 5 days with perfluoroethane, 6 or 8 days with perfluoropropane, and 9 or 11 days with perfluoro-N-butane. Due to its longevity, perfluoro-N-butane appeared to be the most suitable gas for temporary "buckling" of the suprachoroidal space in rabbit eyes.