<p class="abstract"><span lang="EN-US">Adenoid Cystic Carcinoma (ACC) is a rare malignancy of the lung arising from the main bronchial division, sub mucosal glands of large airways. Initially it was suspected as a non-resolving pneumonia, which did not respond to empirical antibiotics. Contrast Enhanced Computer Tomography (CECT) of thorax was suggestive of malignancy, bronchoscopic biopsy was suggestive of adenoid cystic carcinoma. The mainstay of treatment is surgical resection (lobectomy, pneumonectomy). As the tumor is radiosensitive, radiotherapy can be used following surgery in the treatment.</span></p>

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The relationship between infection and asthma is complex. In established asthma, common viral agents, such as rhinovirus, frequently trigger exacerbations, Non tuberculous mycobacterial infection (NTM), I. Material And MethodHospital based observational case control study. Patients having clinical history suggestive of bronchial asthma and fulfilling the diagnostic criteria of difficult to control asthma were included in the study. Each case was matched with two control subjects. Control subjects were chosen as the next two consecutive patient with difficult to asthma attending department of respiratory medicine with difficult to control asthma. Eligible patients after a written informed consent were subjected to a routine clinical examination, blood investigation, chest x-ray, spirometry and contrast enhanced CT with high resolution cuts . Mycobacterial culture of 2 consecutive sputum or bronchoalveolar fluid by MGIT method, including species identification by of the genotype. Clinical and microbiological criteria for diagnosing non tubercular mycobacterial lung diseases(both required)Clinical 1 Pulmonary symptoms, clinical examination and infiltration, nodular or cavitary opacities on chest radiograph or a high resolution computed tomography scan that shows multifocal bronchiactesis with multiple small nodule 2 Appropriate exclusion of other diagnosis. Microbiologicalpossible culture results from at least two separate expectorate sputum sample, if the result from (1) are nodiagnostic, consider repeated sputum AFB examination smear and culture or 2 Positive culture result from at least one bronchial wash or lavage or Trannsbronchial or other lung biopsy with mycobacterial histopathologic feature (granulomatous inflammation or AFB) and one or more sputum or bronchial washings that are culture positive for NTM. Expert consultation should be obtained when NTM are recovered that are either infrequently encountered or that usually represent environmental contamination. Patients who are suspected of having NTM lung disease but do not meet the diagnostic criteria should be followed until the diagnosis is firmly established or excluded. Statistical Analysis:For the test of normality The Kolmogorov-Smirnov test is used as (P value >0.05) were observed in body mass index and FEV 1 data, which showed the normal distribution. While other variable like age, age at onset of asthma, duration of asthma, inhaled corticosteroid dose (ICS), duration of ICS, FEV 1 , FEV 1 /FVC were not found normally distributed. The data were analyzed in SPSS version 20.0 statistical software, Primer and MS Excel.

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