An efficient synthesis of highly substituted pyrrole and bis pyrrole derivatives is reported.

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SummaryThe reaction of 2-[2-(4-fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-pentanoic acid phenylamide with tertiary butyl carbazate and subsequent condensation of the resulting carbamate derivative with a chalcone provided a facile new approach to pyrrolo[1,2-b]pyridazine derivatives.

An Efficient Synthesis of Highly Substituted Pyrrole and Bis Pyrrole Derivatives -[utilizing an acid-mediated Paal-Knorr sequence]. -(SAGYAM, R. R.; VURIMIDI, H.; PADI, P. R.; GHANTA, M. R.; J. Heterocycl. Chem. 44 (2007) 4, 923-926; Dep. Res. Dev., Dr.

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