Therapeutic efficacy of Ruchamax N (M/s Dabur Ayurvet Ltd. India) against digestive disorders in 20 cow of 1 ½ to 3 years was evaluated. Of these, five animals were reported with the history of simple indigestion and rest fifteen with the history of disease induced anorexia & in few accompanied with low milk yield also. The animals were treated with Ruchamax N@ 15 g orally twice daily for 5 days. Clinical signs were recorded so as to assess the time required for complete recovery. On the basis of observations, it was concluded that Ruchamax N is a efficacious in treatment of simple indigestion and disease induced anorexia in cattle.

Clinical examinations were performed on days 0, 3, and 5 of treatment. The respiratory index (Table 1a), based on Research ArticleAbstract | The present trial was undertaken to evaluate the efficacy of a polyherbal formulation, Bovituss ® (M/s Ayurvet Ltd., India), as a supportive treatment for alleviating the clinical signs of respiratory distress. Forty-two cows and shebuffaloes, aging four to nine years of different lactational stages suffering from respiratory tract infection were selected and divided into two equal groups viz. Group 1, receiving standard parenteral therapy with antibiotics and antipyretics, and Group 2, additionally receiving 30 mL Bovituss orally twice daily for a period of five days. The animals were examined on days 0, 3, and 5 of treatment. A significant reduction in the severity of respiratory signs was observed in Group 2. Significant improvement in feed intake was seen only in Group 2 and the overall clinical indices of both the groups calculated for all the three days revealed a significant improvement in Group 2.

<strong>Background:</strong>Terminalia arjuna is being used in various cardiovascular diseases as cardiotonic, diuretic&amp;in hypercholesterolemia. Studies conflict each other for its mechanism of action. This study aims to investigate effect of 90% alcoholic extract of Terminalia arjuna on in vitro isolated rabbit's heart&amp;to find its probable mechanism of action.<p><strong>Objective:</strong> To study the preliminary pharmacological effects of 90% alcoholic extract of Terminalia arjuna in-vitro on isolated heart, coronary blood flow, and to study its probable mechanism of action.</p><p><strong>Material&amp;Methods:</strong> Effect of Terminalia arjuna was observed on heart rate, coronary blood flow, amplitude on in vitro isolated perfused rabbit's heart mounted on langendorff apparatus&amp;further cholinergic&amp;adrenergic blockers were used to study the mechanism of action. Six experiments were conducted for each parameter&amp;data was analysed using Student's t test.</p><p><strong>Results:</strong> Terminalia arjuna causes mean percentage decrease of 7.26%, 9.31%&amp;20.51% in heart rate, decrease of 10.34%, 16.64%, 20.51% in coronary blood flow&amp;decrease of 15.11%, 12.61%, 11.65% in amplitude at 25μg, 50μg&amp;100μg doses respectively. The decrease in heart rate, coronary blood flow&amp;amplitude persists even after cholinergic&amp;adrenergic blockers suggesting that cholinergic&amp;adrenergic receptors are not involved in mechanism of Terminalia arjuna.</p><p><strong>Conclusion:</strong> Terminalia arjuna cardiodepressant effect does not involve cholinergic&amp;adrenergic receptors.</p>