No abstract

The structures of open-chain bis-Reissert analogues and their salts were investigated using I3C NMR spectroscopy. Evidence is presented to show that the former exists in the acyclic form in solution. Detailed structural studies and the I3C NMR data clearly show that, in solution, the open-chain bis-Reissert salt analogues exist predominantly as the amino tautomer.

An open‐chain bis‐Reissert salt analog 5 has been synthesized and fully characterized. The reaction of the salt analog with methyl acrylate yields the pyrrole 7 which exists in solution in the azafulvene form 7a. The reaction of the salt analog with dimethylacetylene dicarboxylate (DMAD) affords the bispyrrole 9.

Propionaldehyde (I), ethylenediamine (II), and KCN are coupled to yield the amino nitrile (III).