BACKGROUND:Many reconstructive surgical procedures have been described for vaginal agenesis. Almost all of them are surgically challenging, multi-staged, time consuming or leave permanent scars on abdomen or skin retrieval sites.AIM:A new simple technique using laparoscopic peritoneal pull-through in creation of neo vagina has been described.MATERIAL AND METHODS:Total of thirty six patients with congenital absence of vagina (MRKH syndrome) were treated with laparoscopic peritoneal pull through technique of Dr. Mhatre between 2003 till 2012. The author has described 3 different techniques of peritoneal vaginoplasty.RESULTS:This technique has given excellent results over a period of one to seven years of follow-up. The peritoneal lining changes to stratified squamous epithelium resembling normal vagina and having acidic Ph.CONCLUSION:Apart from giving excellent normal vaginal function, as the ovary became accessible per vaginum three patients underwent ovum retrieval and pregnancy using surrogate mother, thus making this a fertility enhancing procedure.

The genus Citrus contains a vast range of antioxidant metabolites, dietary metabolites and antioxidant polyphenols that protect plants from unfavourable environmental conditions, enhance their tolerance to abiotic and biotic stresses and possess multiple health-promoting effects in humans along with specifically Immunity boosting. Immunity is described as a condition of being able to resist a particular disease especially through preventing the development of a pathogenic microorganism or by counteracting the effects of its products. The immune system is a bodily system that produces the immune response to defend your body from foreign substances, cells and tissues. The immune system includes various parts of the body including the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (such as those in the gastrointestinal tract and bone marrow), macrophages, lymphocytes including the B cells and T cells and antibodies. This review summarizes various citrus fruit and their bioactive components having a positive effect to promote immunity responses in humans body. Additionally, we highlight the health-promoting properties along with Pharmacodynamic and Phytochemical properties of Citrus fruit described in Ayurveda and their potential usage.

Polycystic ovary syndrome (PCOS) is a common heterogeneous endocrine disorder and about 6% to 20% of women are affected in their reproductive age. Clinical manifestations arise during the early pubertal years, and it’s characterized by irregular menstrual cycles, anovulation, acne, Oligomenorrhea/Amenorrhea, Hirsutism, and frequently infertility. Despite recent advancements in technologies in the scientific world pathophysiology of PCOS is still challenging and initially, most available clinical data communicated findings and outcomes is only in adult women. After that, the Rotterdam criteria are most accepted for adult women and adolescent girls. The diagnostic features for adolescent girls are based on classical tried e.g., menstrual irregularity, clinical hyperandrogenism, and/or hyperandrogenemia. Whereas findings of pelvic ultrasound are significant in adult women but least significant in adolescent girls. Mental health disorders including depression, anxiety, bipolar disorder also occur more frequently in both adolescent girls and women with PCOS. Ayurveda gives prime importance to maintain the healthiness of women and literature provides many references related to signs and symptoms of PCOS in the same way and hence PCOS correlated with Artava kshaya. This review aims to display comprehensive knowledge regarding the pathogenesis of PCOS and Artava Kshaya. The efforts made here will enable earlier identification of girls and adult women with a high propensity to develop PCOS. The timely implementation of individualized therapeutic interventions will improve the overall management of PCOS, prevent associated comorbidities, and improve quality of life. This review emphasizes the various etiological aspects and screening recommendations currently in use to prevent and manages PCOS.