Purpose:To establish the characteristics of secondary retinal and retinal pigment epithelial (RPE) changes associated with the presence of choroidal melanoma and choroidal nevus as documented by optical coherence tomography (OCT) and fundus autofluorescence (FAF).Materials and Methods:PubMed review of major English publications examining the correlation between clinical characteristics of choroidal melanoma and nevus with OCT and FAF findings.Results:The intrinsic properties of choroidal melanoma, as well as overlying RPE changes, drusen, and lipofuscin are best characterized by FAF, while OCT is more sensitive for the identification of subretinal and intraretinal fluid as well as atrophy, degeneration, and photoreceptor loss in the neurosensory retina.Conclusions:Secondary retinal changes associated with choroidal melanocytic lesions can be documented by OCT and FAF. OCT-evident changes are observed more often with choroidal melanoma than choroidal nevus. OCT is better suited to identify the overlying retinal detachment and edema, even before these findings are clinically apparent. FAF is most useful in documenting the presence of lipofuscin, a finding that represents one of the important criteria in differentiating small choroidal melanoma from benign choroidal nevus.
The impact of climate change on humanity and nature is increasingly evident. The atmosphere and oceans have warmed, leading to rising sea levels, a sharp drop in Arctic sea ice, floods, heatwaves, and fires. Calls to action are getting stronger. Concerns about climate change have become a full social movement, stimulating climate activism from the bottom up to the world, especially among young people. Campaigns are initiated by governments and international organizations, scientists and scientific institutions, organizations, groups, and people in civil society, public intellectuals and political, religious leaders, people of culture and entertainment. These campaigns generally aim to inform, raise awareness and shape public understanding about the science, problems, and policy of climate change, with the hope that, first of all, people will change their attitudes and behavior, and secondly, will mobilize to put pressure on policymakers for effective climate policies.
The communication in the field of health can be defined as a communication strategy used to inform and influence individual and community decisions with the aim of improving and enriching personal and community behaviors and public health practices. It includes studying public health attitudes and behaviours to determine the type, frequency and format of the messages.
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