The 5's technique is an assemblage of working tools of lean manufacturing that organize, order, clean, standardize and continuous any workplace. This article exemplifies a case study on the implementation of the Lean 5's Technology in a micro, small and medium enterprise (MSME), so as to make it more efficient, effective and productive. Considering the working conditions, a 5's framework has been analyzed and implemented where a remarkable improvement was noticed in product quality, lead time as well as cost reduction. The personal study clearly exhibits that it is very essential for an organization to train its workers about 5's rules. In this article, an attempt has been made to identify various shortcomings and mitigate them. The proposed framework investigates the flaws in the manufacturing processes within the organization. Standard operating procedures have been developed and applied on the shop floor holistically and changes were recorded which validates the fact that 5S is a simple and powerful technique, used to eliminate the process wastes, errors and helps in the development of a formal workplace organization system for the company. Furthermore, various barriers faced during the implementation of 5S rules were identified and a through the technique of Interpretive Structural Modelling (ISM) a visual model was developed which showcased the various interrelationships existing between the said barriers