The medicinal plants are important source for pharmaceutical manufacturing. Medicinal plants & herbal medicines account for a significant percentage of the pharmaceutical market. There is increasing awareness and general acceptability of the use of herbal drugs in today’s medical practice although most of these applications are not scientific. Herbal medicines are not a simple task since many factors influence the biological efficacy and Reproducible therapeutic effect. So it is necessary to improve safety of herbal drugs by developing certain quality control parameters & by following the WHO guidelines for herbal medicines. This review seeks to enlighten the need to establish quality parameters for collection, handling, processing and production of herbal medicine as well as employ such parameters in ensuring the safety of the global herbal market. It is necessary to introduce measures on the regulation of herbal medicines to ensure quality, safety, efficacy of herbal medicines by using modern suitable standards & GMP. The processes of good quality assurance and standardization of herbal medicines and products using various spectroscopic, chromatographic and electrophoretic methods were also discussed. In fact, the research field of quality control of herbal medicines is really an interdisciplinary research. It needs crossover of chemistry, pharmacology, medicine and even statistics to provide a platform for the quality control of traditional herbal medicines and further to discover the novel therapeutics composed of multiple chemical compounds. Keywords: Herbal drugs, Adulteration, Standardization, Chromatography, Electrophoresis, HP-LC and GC-MS.

Many indigenous Indian medicinal plants have been found to be successfully used to manage diabetes and some of them have been tested and active principles isolated. However, search for new antidiabetic drugs for effective treatment is on. The vast majority of people on this planet still rely on their traditional material medica (medicinal plants and other materials) for their everyday health care needs. It is also a fact that one quarter of all medical prescriptions are formulations based on substances derived from plants or plant-derived synthetic analogs. The herbal drug from tribal region is selected for the study which is used for diabetes andliver diseases. Pergularia daemia (Asclepiadaceae) is a perennial herb growing widely along the road sides of India. It has been used in folk medicine for the treatment of Dibetis mellitus &liver disorders. It is widely distributed in the tropical and sub tropicalregions of the world. Various phytochemical including terpenoid, flavonoids, sterols and cardenolids have been isolated andidentified from the various parts of the plant (leaves, stems, shoots, roots, seeds and fruits whole plant). P. daemia widely used by various tribal communities in Western Ghats of India for the treatment of variety of ailments, while predominantly the roots of theplant have been used to treat liver disease and jaundice.The present review article aims towards medicinal Pharmacological potential, Bioactive remedies, Phytochemical profile and other important aspects of P. daemia. Keywords: Ethnobotanical uses, Pergularia daemia, Pharmacological Profile, Phytochemical Profile

Thyroid disease is a major issue all over the world. Thyroid illness is also very common in India. Numerous thyroid disease studies have revealed that 42 million Indians are affected by the disease. Thyroid ailments are classified into five types in India: hypothyroidism, hyperthyroidism, goitre and iodine deficiency disorders, Hashimoto's thyroiditis, and thyroid cancer. The epidemiology of these five diseases will be the subject of this review. Thyroid hormone replacement therapy has been used to treat hypothyroidism for over a century. For the majority of the twentieth century, the first pharmacological treatments were natural thyroid preparations (thyroid extract, desiccated thyroid, or thyroglobulin), which contained both thyroxine (T4) and triiodothyronine (T3) (T3). This article discusses briefly the current treatment options for common thyroid issues.

the primary objective of cloud storage is to maintain data integrity, which involves implementing measures to prevent unauthorized access and ensuring that data can be regenerated if mishandled. To achieve this, a proxy server will be assigned the task of protecting and restoring data in case of unauthorized modifications. Users' data will be stored in both public and private areas of the cloud, with only public data being accessible to users and private data being kept more secure. Cloud storage offers users various redundancy configurations to balance performance and fault tolerance, with data availability being critical in distributed storage systems, especially when node failures are common in real-life scenarios. In this research, a proposed aes 128 encryption algorithm and role-based access control (rbac) scheme are explored to provide secure data storage and sharing, as well as a secure user access policy. Additionally, a backup server approach is used as a proxy storage server for ad hoc data recovery for all distributed data servers. The experiment's analysis is proposed in both public and private cloud environments, utilizing keywords such as rbac, elgamal encryption scheme, proxy key generation, advanced encryption standard (aes), and more