Herbal products are increasingly used against lipid to attenuate its negative impact on vasculature system. However, there are uncertainty regarding the best administration approaches and preparation of herbal product to be used due to variation in absorption rate and extent with subsequent impaction on the lipid levels. The aim of the present study was comparing the pharmacological and analytical aspects of soaked versus powder form of Hypericum perforatum; a well-known anti-hyperlipidemic herbal product, using atorvastatin drug as a reference drug for comparison in addition to controlling groups (on/off lipid diet) handled as an additional control group. To conduct this research, the hyperlipidemia mice models were created by exposing the mice to a fatty diet and using H. perforatum and atorvastatin for evaluation. The plant extracts were also analyzed for active constituents. The results indicate that the plant analysis detected the presence of different antihyperlipidemic agents and the plant has effectively reduced plasma lipid parameters in exposed mice compared to control group; especially when taken forms of the plant was used. The study concluded that; soaked H. perforatum extract shown an effective reduction of lipid parameters and analysis of which revealed the presence of herbal active constituent which might be utilized in industrial pharmacy for new drug innovation.

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The purpose of this research article is to explore the coordination chemistry and antibacterial activity of six new mononuclear complexes formed via reacting Ag(I), Zn(II), and Mn(II) ions with the Schiff base as a ligand (Nicotinamide- semicarbazone) in a (1:2) ratio in both acidic and basic medium., the six complexes are characterized by elemental analysis(CHN), atomic absorption spectroscopy, Infrared spectroscopy, (1H NMR). and different Technique such as melting point, conductivity measurements, Molar refraction The suggested formula of the complexes were [M(NASC)2] Xn in natural medium and [M(NASC)2] in basic medium, M = Ag n=1, M= Zn, Mn n=2, X=NO3 NASC = Nicotinamide- semicarbazone. It was a tridentate ligand it coordinated onto metal ions via three nitrogen atoms, producing off white or yellow complexes with only an octahedral geometry. These complexes and their ligands were evaluated as antibiotics against a series of medically significant bacteria, and both were found to be very effective.

Copper (II) and Zinc (II)Complexes with O-nitrobenzylidenetrimethoprim were prepared. The complexes were identified by employing Technique of CHNS analysis , molar conductance, magnetic susceptibities and spectral measurements (FT-IR electronic he above ligand formed ionic complexes having general T ,