Cincau Hijau leaves (Cyclea barbata L.Miers ) has been used empirically as a medicinal plant because it contains many potential compounds such as flavonoids. Cincau Hijau leaves has been known as antioxidant activity. Determination of pharmacognosy parameters and phytochemical screening of dry leaves and extracts have been carried out as well as determination of total fl avonoids content. Fresh leaves were extracts with water and Dry leaves were macerated with 96% ethanol and were then concentrated by rotavapor to obtain viscous extracts. Free radical scavenging activity of the extracts was evaluated using DPPH method. Afterwards, determination of specifi c and non-specifi c parameters were performed. Results of phytochemical screening of powder and 50% and 96% ethanol extract showed that tall the tested samples contained alkaloid, fl avonoids, saponins, tannins, steroids/ triterpenoids, coumarin. The examination of specifi c parameter showed that the extract has a thick consistency, tawny color, bitter taste, characteristic odor. In addition, water-soluble compound and 96% ethanol extract are 46.64 and 62.13% respectively whereas ethanol-soluble compounds are 39.22 and 74.72%, respectively. While the results of nonspecifi c parameters of 50% and 96 % ethanol extract displayed total ash content of 9.69 and 9.49%, respectively, acid insoluble ash content of 0.30 and 0.16%, respectively, content of water soluble ash of 9.17 and 4.30%, respectively, loss on drying of 9.35 and 8.9%, respectively, water content of 8.45 and 7.25%, respectively. Based on heavy metal contamination, Pb concentration in 50 and 96% ethanol extract are 0.0227 and 0.0333 mg/kg, respectively whereas Cd concentration are 0.1206 and 0.0022 mg/kg, respectively and total number of CFU of 4,22 x 103 and 2,30 x 103 colonies/g, respectively while molds and yeasts number of colony of 0,48 x 102 and 8,88 x 102 colonies/g, respectively. Moreover, the total flavonoid was 0,19 %. Result of DPPH inhibition test showed that IC50 96 % ethanol extract are 83,280 ppm and water extracts are 102,01 ppm

Problem solving merupakan salah satu keterampilan penting yang harus dimiliki siswa untuk mengahdapi perubahan dan masalah yang kompleks di abad 21. Tujuan dari penelitian adalah untuk meningkatkan problem solving skills siwa kelas 12th menggunakan modul mutasi genetik berbasis creative poblem solving. Penelitian ini merupakan penelitian tindakan kelas yang berlangsung dalam dua siklus, dilaksanakan pada bulan Januari sampai Februari 2023. Setiap siklus terdiri dari 4 tahap: perencanaan, pelaksanaa, observasi dan refleksi. Partisipan penelitian adalah 24 siswa kelas 12 SMA Negeri 3 Ciamis. Data penelitian diperoleh melalui tes problem solving skills, wawancara dan observasi aspek keterampilan dan sikap. Targer penelitian adalah naiknya rata-rata persentse setiap aspek sekitar 30%. Hasil penelitian menunjukkan persentasi rata-rata problem solving skills siswa naik dari 36,93% menjadi 85,68%. Berdasarkan hasil penelitian dapat disimpulkan bahwa modul mutasi genetik berbasis creative poblem solving dapat meningkatkan problem solving skills siswa.