Dermatological findings are frequent during the first days of life and some of them characterize the newborn's skin. Mixed-race newborns and those whose mothers had some gestational risk factor had more dermatological findings. The gestational age, newborn's ethnicity, gender, Apgar at the first and fifth minutes of life, type of delivery, and seasonality influenced the presence of specific neonatal dermatological findings.
We report a case of an 80-year-old Brazilian man, farmer, with lesions on the dorsum of the hand. A direct mycological examination, cultivation and microculture slide observation was performed. The sequencing of ITS1-5.8S rDNA-ITS2 region was carried out and the etiological agent confirmed as Exophiala spinifera. The in vitro susceptibility of this isolate to antifungal agents alone and in combination was evaluated. This is the third case of phaeohyphomycosis caused by Exophiala spinifera in Brazil.
Papular elastorrhexis is a rare acquired disease, first described in 1987 by Bordas, which has been very rarely reported in the literature. It is characterized by small asymptomatic non-follicular papules, mainly distributed in the trunk. Histology of the lesions shows homogenization of collagen and fragmentation of elastic fibers in the dermis. The rarity of this disease is probably due to the subtlety and benign nature of clinical and histopathological alterations, which can be easily confused with other pathologies. The authors report the case of a patient with exuberant clinical manifestations typical of elastorrhexis papular.
BackgroundThe worldwide incidence of cutaneous melanoma (CM) has been continuously
increasing over the last decades. Primary and secondary prevention, with
attention to risk factors and early diagnosis, remain the cornerstone for
reducing the burden of cutaneous melanoma. Detailed information with respect
to clinical and pathological data on cutaneous melanoma is scarce in
Brazil.ObjectiveThe purpose of our study was to analyze epidemiological and pathological
characteristics of primary cutaneous melanoma in Joinville, southern
Brazil.MethodsObservational, cross-sectional, retrospective study in which 893 reports of
primary cutaneous melanoma from the local population were analyzed in the
period 2003-2014. The study was approved by the local Ethics and Research
Committee.ResultsWe observed a female predominance of cutaneous melanoma (56.3%). The age
standardized incidence rate of primary cutaneous melanoma for the world
population in the period 2003-06 was 11.8 per 100,000 population (CI 95%,
10.3-13.4), and 17.5 (CI 95%, 15.7-19.3) in 2011-14, revealing a significant
increase of 48.3% (p < 0,05). Six and a half percent of patients had
multiple cutaneous melanomas (mean 2.2 years and a maximum of 10.0 years
between diagnoses). We observed significant differences between the location
head/neck and cutaneous melanoma in situ, lower limb with Breslow depth S
III and upper limb with Breslow depth S I. The comparison of the
characteristics of cutaneous melanoma in the elderly and non-elderly (<
60 years old) showed significant differences with respect to all the
variables studied.Study limitationsUsing secondary data source.ConclusionJoinville has high incidence coefficients for Brazilian standards, showing an
increase in the incidence of cutaneous melanoma.
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