INTRODUCTION: Ovarian Cancer (OC) is the first death cause by gynaecological cancer in developed countries and the third cause of gynaecological cancer in the world. Detecting irresectable disease is crucial to select surgical candidates and Peritoneal Carcinomatosis (PC) depiction helps to get a complete debulking without residual disease >1cm, the best prognostic predictor in advanced OC. CT is the elective technique for abdominal imaging, although its accuracy for PC in OC and cytoreduction success prediction ability is limited. PET/CT is considered for systemic evaluation in OC however, it is not a reference standard for PC. PC presents as high signal foci in DWI, with higher contrast than conventional MRI. Whole Body DWI with Background Suppression MRI (WB-DWIBS/MRI) combines conventional anatomic with Diffusion Weighted Imaging (DWI). This study aims to assess the diagnostic performance and tumour burden correlation of WB-DWIBS/MRI in ovarian PC using PCI, referred to cytoreduction surgery as standard reference. MATERIAL AND METHODS: Our local ethical board approved this prospective study and all participants signed written informed consent. 50 out of 217 consecutive patients with disseminated primary or recurrent OC were eligible for cytoreduction and WB-DWIBS/MRI. Peritoneal Cancer Index (PCI) scores (0-3) tumour burden in 13 anatomical regions, hence global ranging 0-39. Two radiologists (R1 and R2) preoperatively assessed PCI and the gynaecologic-oncologist team after. Diagnostic performance was calculated for each of the PCI regions and globally. We evaluated interobserver agreement using Cohen´s Kappa, statistic differences with the *Manuscript containing Abstract, Sections and References (Without corresponding author details) Click here to view linked References

Diagnosing the absence or presence of peritoneal carcinomatosis in patients with gastric cancer, including its extent and distribution, is an essential step in patients’ therapeutic management. Such diagnosis still remains a radiological challenge. In this article, we review the strengths and weaknesses of the different imaging techniques for the diagnosis of peritoneal carcinomatosis of gastric origin as well as the techniques’ imaging features. We also discuss the assessment of response to treatment and present recommendations for the follow-up of patients with complete surgical resection according to the presence of risk factors of recurrence, as well as discussing future directions for imaging improvement.

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