Viral warts of the skin are benign epidermal growths caused by infection with human papillomavirus (HPV). Some warts may have bad cosmetic appearance and may be destructive as in periungual warts or painful as in palmoplantar warts. 1 Also, recalcitrant warts continue to enlarge and multiply, resulting in more liability of spreading of infection that may make patients suffer from physical embarrassment and psychosocial distress, and also present a therapeutic challenge even for Dermatologists. 2 Resolution of warts can be occurred spontaneously in a high percentage of patients (60%-65%) within 1-2 years but, recalcitrance of warts may appear in about one third or more. 3 There is no specific definition of recalcitrance, but typically, recalcitrant
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