In children, commonest liver tumor is hepatoblastoma. We present a 14-month-old male child who presented with abdominal distension and loose stool. Radiological imaging revealed solid hepatic mass. Hematological investigations revealed anemia, thrombocytosis and high Serum alpha fetoprotein (AFP) level. Ultrasound (USG) guided FNAC confirmed the mass to be hepatoblastoma. CT scan revealed hepatoblastoma PRETEXT stage III. The patient underwent 6 cycles of neoadjuvant chemotherapy and responded to POSTTEXT stage II. Left hemi-hepatectomy was done with clear resectin margins. Complete surgical excision of the mass after preoperative chemotherapy remains the mainstay of the treatment of locally advanced hepatoblastoma.

Pancreatic Adenosquamous Carcinoma is a rare subtype of pancreatic cancer. Here we present a 51 year old man who presented with features of obstructive jaundice. Radiological imaging studies revealed the presence of solid pancreatic mass. He underwent pancreaticoduodenectomy – superior mesenteric artery (SMA) first approach. Postoperative period was complicated with prolonged ascitic drainage. Histological analysis suggested adenosquamous carcinoma with 30% squamous components, pT2N0M0. Patient is being planned for adjuvant chemotherapy.