Background: The article presents experimental studies conducted on Wistar rats in the amount of 50 individuals. An artificial gum recession defect was created.Aim: to evaluate the effectiveness of creating a gum recession model in the proposed way.Material and methods: Experimental animals at the beginning of the study had an intact oral mucosa: pale pink color, without pathological changes. An experimental model of gum recession was created by excision of V-shaped periodontal tissues from the vestibular surface in the area of the lower jaw incisors of a rat, then a DispodentPak No. 000 retraction thread was applied in the area of the lower central incisors in the circular ligament of the tooth to a depth of 1.5 mm, and Vitrebond dental glass ionomer cement was applied to the vestibular surface of the neck of the tooth of the lower incisors, with at the same time, prednisone is administered intramuscularly at the rate of 12 mg / kg of animal weight on the 1st, 3rd and 5th day. For the experiment, female white rats in the amount of 50 individuals were used as a model. All animals were divided into 2 groups depending on the method of creating a gum recession defect. In the control group of rats, the defect was created according to the standard procedure by conducting a V-shaped incision.Results: When creating the proposed model of experimental gum recession, the clinical and pathomorphological picture is achieved under the influence of local factors: V-shaped gum incision, retraction thread, dental glass ionomer cement. To suppress the processes of self-regeneration of the gums, the optimal dose of prednisone is administered.Conclusions: On the 3rd day of the experiment, a V-shaped defect was observed in animals. On the 10th day, clinical signs of gum recession are determined: a defect with a depth of 2 mm. The average depth of recession in animals was (2 ± 1.7 mm). A relatively short process of modeling a gum recession (no more than a month). In this case, a local lesion of the gum is created, not burdened by any other pathology in the animal, and having both local and general (stress) pathogenetic factors, against the background of changes in the reactivity of the organism, which corresponds to the modern theory of the occurrence of recession as a polyethological disease in humans.

The article presents experimental studies conducted on Wistar rats, in the amount of 50 individuals. The creation of an artificial gum recession defect was carried out. Application of SANS MOTS oil to the defect area for 20 minutes containing marque blanche phytoconcentrate with phytosterols, the course of treatment was 5 procedures, with an interval of 2 days.

The discovery of stem cells is considered one of the most important achievements of mankind. The ability of any stem cells to produce different cell types makes them a very convenient system for studying the molecular genetic events that cause cell differentiation. Due to their ability to differentiate into any tissue, stem cells can be used to treat a huge number of diseases. Therefore, the comprehensive study of stem cells is one of the most relevant and promising areas of modern medicine.

BACKGROUND: Inflammatory periodontal diseases are an important medical and social problem, since more than 90% of the adult population of the Russian Federation suffer from this pathology. AIM: The work is to study the effectiveness of the treatment of chronic catarrhal gingivitis in employees of a limestone mining enterprise based on clinical and microbiological methods. MATERIALS AND METHODS: We examined 214 employees aged 2227 years (machinists, crushers, sorters and workers of the administrative and economic part) working at a limestone mining enterprise (Ufa). Chronic catarrhal gingivitis was detected in 61 patients. To determine the effectiveness of treatment by randomization, patients were divided into the 1st (main) group (n=31) with chronic catarrhal gingivitis, who were prescribed the treatment recommended by us, and the 2nd (comparison) group (n=30) with chronic catarrhal gingivitis, who were treated with basic therapy. Clinical studies were conducted according to the standard scheme and recorded in the medical history. anamnesis was collected, dental formula, plaque, swelling and hyperemia of the gums were registered during the dental examination, bite and occlusive contacts were evaluated. The following indices were used: hygienic, bleeding, papillary-marginal-alveolar (PMA). RESULTS: Clinical and functional data of these patients were obtained. A microbiological assessment of the gingival fluid content is given. Issues of the diagnostics and treatment of patients with chronic gingivitis (catarrhal) with the use of a drug based on lactobacilli and bifidobacteria and Placentol are considered. The effectiveness of the treatment has been determined. CONCLUSION: The proposed method using resorption of Smart candies and rinsing with Placentol balm in patients with chronic catarrhal gingivitis working at a limestone mining enterprise is more effective and can be included in the protocol for the treatment of patients with chronic catarrhal gingivitis working at limestone mining.