BACKGROUND: Drug-related problems (DRPs) and errors occur frequently in general health and pediatric care due to several reasons. AIM: This study aims to determine the DRPs incidence in pediatric inpatients utilizing antibiotics in Universitas Sumatera Utara Hospital, Medan, Indonesia. MATERIALS AND METHODS: It was carried out in May–July 2019 using a retrospective cross-sectional method and the data obtained from June to December 2018. RESULTS: In the aforementioned hospital, the medical records of patients were 575 among which 135 (23.47%) met the inclusion criteria and the males, 84 (62.22%) were higher than females. Furthermore, majority of them, 55 (40.74%) were 5–11 years old, and 86 (63.70%) had a maximum stay length of ≥5 days. There were 73 DRPs events in 37 patients, namely, 46 (63.01%) low doses, 22 (30.14%) overdoses, 2 (2.74%) side effects of drugs, and 3 (4.11%) drug interactions. The most experienced antibiotic DRPs were in cefotaxime 14 (19.17%) and the most diagnosed was in appendicitis 14 (10.37%) utilization. CONCLUSION: There were antibiotic DRPs in pediatric inpatients in Universitas Sumatera Utara Hospital, Medan.

Objective: The aim of this study was to determine antibiotics prescribing profile for pediatric outpatients in Universitas Sumatera Utara Hospital, Medan, Sumatera Utara (Indonesia) in 2018.Methods: This study was using a retrospective cross-sectional method study which conducted from March to April 2018 with data from January to December 2018. From Universitas Sumatera Utara Hospital, there are 211 prescriptions contained antibiotic that made as sample. The antibiotic analyzed based on the group, type, duration of administration, and dosage-drug form along with the dose.Results: The antibiotic that mostly prescribed for pediatric outpatients was antituberculosis for 211 prescriptions (72.99%) which is isoniazid. There are 15 prescriptions (7.11%) with mismatch the duration of use. From 211 prescriptions with complete data to assess the dose, there are 75 prescriptions (35.55%) with mismatch dose and the most dosage form is pulveres for 121 prescriptions (57.35%).Conclusion: It shows that isoniazid was the most prescribed antibiotic for pediatric outpatients in Universitas Sumatera Utara Hospital, Medan, and there is still mismatch in dose and duration of use in antibiotic prescribing for pediatric.