The carbon footprint calculation of a university is considered a model role for the rest of other organizations to follow. It is because that a university is full of talented people with diverse experience, advanced research facilities and it consists of many resources that we need to measure, manage and report greenhouse gas (GHG) emissions [1]. In this study, tier 1 methods of the Intergovernmental Panel on Climate Change (IPCC) and setting boundaries method of the World Resources Institute (WRI) and World Business Council for Sustainable Development (WBCSD) are applied for calculating GHG emissions from Esentepe Campus of Sakarya University (SAU) in 2015. In the calculation of this study, the last updated Global Warming Potential (GWP) from the IPCC Fifth Assessment Report, 2014 was used for converting greenhouse gases into CO2 equivalent [2]. As a result, Esentepe Campus of Sakarya University released 12,330.73 tons of CO2 equivalents (Expressed as tCO2e) and scope 2 indirect emissions of purchased electricity is the most important emission source, followed by emissions from student and employee commuting. In order to reduce CO2 on Campus, some solutions are also suggested for efficiently consuming electricity and energy.