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Thiazolidines are five-member heterocyclic having sulfur, nitrogen, and oxygen atoms in their ring structure and exhibiting potent as well as wide range of pharmacological activities. In this minireview, recent updates on synthesis and pharmacological evaluations of molecules based on 2,4-thiazolidine and rhodanine are discussed.

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Heterocyclic Chemistry is the backbone of medicinal compounds that exhibits numerous biological activities. Pyrazole and its derivatives possess nitrogen atom along with carbon atom as a substitution and show a diversity of biological activities such as antibacterial, antimicrobial, anti-inflammatory, antioxidant, antidiabetic, anticancer, antifungal, antidepressant, anticonvulsant, analgesic, and monoamine oxidases (MAOs)as shown by pyrazoline prepared from chalcone(Intermediate). The synthesized compounds are checked by the TLC and further analyzed by the IR, NMR, and UV spectroscopy.

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