An improved green route has been developed for the oxidation of sulfide compounds. Albendazole is converted to ricobendazole or albendazole sulfone using H 2 O 2 as an oxidant and H 2 O as the solvent. High yields of the corresponding products were obtained by carrying out the reaction at room temperature. This synthetic method is environmentally clean and safe, operationally simple for the oxidation of other benzimidazole anthelmintics and various sulfide compounds.
An efficient and green method has been developed for oxidation of aldehydes to carboxylic acids by employing deep eutectic solvent (DES) (ChCl:Urea) as a green solvent in the presence of H2O2 as an oxidant at ambient temperature. Numerous aldehydes were oxidized to give corresponding carboxylic acids with exceptional conversion and selectivity under catalyst free conditions. Sustainable approach, use of green solvent (ChCl:Urea) and good to excellent yield of products make this method greener and unconventional over other reported procedures.
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