Antioxidants play a very crucial naturally role in our bodies. Still, unfortunately, that is not enough. We need to compensate for the shortage we face by increasing the dietary antioxidants as exogenous sources, especially when there is an exogenous factor-induced oxidative stress as with the medical radiology staff because how much ionizing radiation they are exposed to exceeds the primitive dose limit by the International Commission on Radiological Protection (ICRP). Thus, a suitable uptake of minerals, vitamins, and Combinations of dietary antioxidants through the daily diet and balanced it remains the promising approach without exceeding the uptakes doses that could reverse the positive effects of this approach. This review focuses on the present knowledge about dietary antioxidant sources, mechanisms, effects of the cell components. It critically investigates studies examining the effects of dietary antioxidant supplementation and its role among medical radiology workers.