Purpose: to study the dynamics of the morphofunctional state of students during expanding fitness means in physical education classes. Materials and methods: students at the University of Economics (n = 820, age 18.0 ± 0.76 years) took part in the study. The experiment was lasting for 36 months. With students of group N1 (n = 386), traditional classes were conducted in accordance with the current physical education program. Development of physical education in group N2 (n = 434) was carried out by increasing the means of fitness and daily monitoring of physical activity with modern devices. Functional diagnostics was carried out on the hardware-diagnostic complex «Esteck System Complex». «Omega-M» hardware and software complex was used for studying biological rhythms. The evaluation of working capacity of the cardiovascular system was determined using the Ruffier test. Results: in group N2, authentic differences were determined in the adequacy of the regulation processes, the integral indicator of the sports shape, the level of physical activity (the number of steps per day). In group N1, authentic differences were determined only in the level of physical activity. At the same time, there was no significant improvement in the morphofunctional state in the groups. Conclusions: thanks to the expansion of fitness means, the provision of an individual-typological medical record and the stimulation of physical activity, it was managed to achieve a positive dynamic of the morphofunctional state of students of group N2.