Background & Objective: The objective of this study was to determine the association between the maternal serum concentration of PAPP-A and free B-HCG at 11-13(+6) weeks and the uterine artery pulsatility index (PI) at 30-34 weeks with the prediction of preeclampsia. Materials & Methods:This cohort study was performed on 882 women with singleton pregnancies from March 2018 to November 2020 at the university hospital (referred center) in Ahvaz/Khuzestan. Maternal serum PAPP-A and free B-HCG at 11-13(+6) weeks and uterine artery PI at 30-34 weeks were measured and compared between women with and without PE. MOM PAPP-A<0.4, MOM-free B-HCG>3, and uterine artery pulsatility index >1 (>95%) were considered abnormal. Then The effect of each of the indicators on preeclampsia was determined by overlaying the layers and performing logical calculations in ARC GIS software. The distribution of PE in different cities of Khuzestan province was investigated. Results:The mean MOM PAPP-A was significantly lower (1.05 vs. 1.21 P=0.03), and uterine artery PI was significantly upper (0.93 vs. 0.88 P<0.01) in preeclamptic women compared to women without PE. No significant differences were observed in the mean MOM-free B-HCG between women with and without PE (1.33 vs. 1.2 P=0.667). The highest percentage of PE was in two regions of Ahvaz (80%), but concerning women referred from different cities was in Andimeshk (75%). Conclusion:A low level of maternal serum PAPP-A and increased uterine artery PI promoted the chance of developing PE. The highest prevalence of PE was in two regions of the center of Khuzestan province, and the most preferred due to PE in different cities was in Andimeshk.

Objective: To evaluate the success rate of laparoscopy and hysteroscopic Dilation &amp; Curettage in treating cesarean scar pregnancy. Methods: This cross-sectional study was carried on patients suspicious to CSP referred to Imam Khomeini Hospital, Ahvaz from Jun 2016 to March 2018. Gestational site was carefully evaluated by hysteroscopy and then curettage was carried out under laparoscopic guidance. The primary outcome in the study was time interval from treatment to hCG resolution. Moreover, the secondary outcomes were vaginal bleeding time and residual mass size. Results: In this study, 30 women with intrauterine CSP were evaluated. Of these, 5 had live embryos and 25 had dead fetuses. The success rate of treatment was 100%. Only one patient needed to transfusion. The mean and median duration of Bhcg resolution were 30.9 and 28 days, respectively. Moreover, The mean and median duration of vaginal bleeding were 30.9 and 28 days, respectively. The mean level of residual mass was 9.8 mm3 (ranged from 1 to 25 mm3). Conclusion: Overall, the findings of this study showed that D&amp;C effectively treated CSP patients (100% success rate), reduced the time of Bhcg resolution and also reduced vaginal bleeding time.