Cardiovascular complications in ST-segment–elevation myocardial infarction survivors remain substantial despite advances in the management of STEMI. We aimed to determine effect of AH on the area at risk (AAR), final infarct size (FIS), and salvage index (SI) in STEMI patients using cardiac magnetic resonance (CMR). 43 successfully reperfused STEMI patients were recruited. CMR was utilized to estimate AAR and FIS, SI was calculated: SI = AAR- FIS/AAR. AH showed significant positive correlations to FIS ( r -value = 0.538, P = < 0.001), and AAR ( r -value = 0.435, P = 0.002), and a negative correlation with SI ( r -value = −0.378, P = 0.006).