Introduction: Peptic ulcer Complications of peptic ulcer disease is a life threatening complication it needs special attention with prompt resuscitation and appropriate surgical management if morbidity and mortality are to be avoided. Aims: Aimed to study surgical management of the various causes of duodenal perforation to try to recognise the predictors of outcome in such patients. Materials and methods: It is a prospective study done in department of general surgery study from April 2018 to September 2019 with 50 patients with diagnosis of perforated peptic ulcer disease, above 20-70 years of age, patients consented for study and patients presenting with complications of PUD like upper GI bleeding, peptic ulcer perforation and features of gastric outlet obstruction were included. Results: In present study the peak incidence was in the 4 th decade (31-40 years). The majority of patients, 23(46%) were younger than 40 years. Post-operative complications were recorded in 14 (28%) patients. Of these, surgical site infection (16%) was the most common post-operative complications. The mean age of patients who developed complications was 53.4±15.1 years. Premorbidiy illness, treatment delay and nature of perforation are significant Predictors of complications. Conclusion: Perforation of peptic ulcer remains a frequent clinical problem in our environment predominantly affecting young males not known to suffer from PUD.