We report the fourth case reported world-wide of an intravenous pyogenic granuloma (IVPG) originating from a renal vessel. This rare and benign tumor is mostly found in the head and neck region and has been described very rarely in association with the kidneys. By reviewing the characteristics of all published cases we suggest diagnostic and therapeutic strategies for patients with possible IVPG in the renal vessels out of the view of highly experienced surgeons specialized in advanced Inferior Vena Cava-thrombectomy.