The aim was to study the abnormal menstrual patterns of adolescent girls, the cause of dysfunction, and the associated factors in relation to the menstrual disorders. MATERIAL & METHODS: A prospective study done in department of obstetrics & gynaecology SMS Medical College from June 2010-June 2012. 120 adolescent girls between 12-19 yrs of age with menstrual disorders excluding dysmenorrhoea, primary amenorrhoea &pregnancy related bleeding problems were included in the study. After detailed history, examination all had an ultrasound, thyroid profile & serum prolactin levels. Other investigations done if required according to clinical profile of the patients RESULTS: 50% of the girls presented at 18-19 years. 83.3% attained menarche between 12-14 years of age Menorrhagia & oligo-hypomenorrhea were the most common dysfunction, i.e 26.7% each, abnormal investigative profile was more common in patients with oligo hypomenorrhea, 40% of patients with oligo and/or hypomenorrhea had PCOS, 14% had hyperprolactinaemia,7% had hypothyroidism. 1/3 of these patients had normal hormonal & USG findings. Majority (72.2%) of the patients with menorrhagia and /or metrorrhagia had normal hormonal and USG findings. CONCLUSIONS: Evaluation of bleeding problems in adolescents is justified, before considering them as normal physiological transition. Although most problems are explained by anovulation other causes must be considered & excluded Hormonal evaluation of these patients is justified & reveals unsuspected pathology.
OBJECTIVES: To investigate whether endometrial thickness on the day of hCG administration is a predictor of intrauterine insemination (IUI) success. MATERIAL AND METHODS: Three hundred and eighty women undergoing IUI cycles are analysed for Endometrial thickness on the day of hCG administration, Endometrial thickness measurement was done on the day of HCG administration. Correlation between endometrial thickness and factors such as age, dominant follicle numbers, stimulation protocols and pregnancy rate were assessed& compared between pregnant and non pregnant patients. A similar comparison was made between ongoing pregnancies and those that resulted in a loss in a University hospital-based infertility center from Dec 2011-Nov 2012. Main Outcome Measure(s): Endometrial thickness versus IUI outcome. RESULTS: In 220 couples, 365 cycles performed. Pregnancy rate was 14.5%. 90% of pregnancies were ongoing. The mean age of females was 28.6 & mean ET was 8.1mm +-1.47. The mean ET in age range 17-25 yrs was 7.4±1.98 mm and in age range of >40 years was 6.9±1.7 mm (p=0<001HS). With increasing the number of 16-18 mm follicles pregnancy rate was 16%, 11% &15.6% with 1,2 & >3 follicles . No statistically significant correlation was found between the two. INTRODUCTION:To obtain a higher likelihood of achieving pregnancy, IUI is usually synchronized with ovulation, either in a natural or a stimulated cycle. The overall success of IUI varies, with pregnancy rates between 5 and 26% per cycle (1). During ovulatory cycles, pattern and thickness of endometrial is variable. After menstruation, endometrium is thin and becomes thicker gradually. Although many studies were done about affecting factors on endometrial thickness in infertile women, over the years, but the results is still unclear ( 2 ,3).The aim of this study was to determine the effect of some factors such as age, number of follicles on the endometrial thickness and its impact on pregnancy in intrauterine insemination cycles. OBJECTIVE:To discover the factors contributing to endometrial thickness, and to assess the impact of endometrial thickness on pregnancy rates (PRs) according to these factors. MATERIAL &METHODS:In this study we have evaluated a total of 365 IUI cycles at SMS Medical College Jaipur (Dec 2011 to Nov 2012 infertile women considered for intrauterine insemination (IUI). Endometrial thickness measurement was done on the day of HCG administration. Cycles were natural/stimulated with letrozole 5 clomiphene citrate and/or gonadotrophins (HMG/FSH). Letroz5 50-100 mg clomiphene citrate (D3-D7), followed by 75-150 IU of gonadotrophins added Correlation between endometrial thickness and factors such as age, total follicle number and pregnancy rate were assessed. Ovarian (Follicle maturation) and endometrial responses monitored by serial TVS D9-13. 5000-10000 IU HCG administered (when at least one follicle mean diameter was >18 mm. On the day of hCG administration, TVS scan measure endometrial thickness &
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