Classic and high-frequency ultrasonographies are useful methods for monitoring anti-cellulite therapies.

Detailed molecular structural studies of new polymeric delivery systems of lipoic acid were performed by ESI-MS. ESI-MS proved to be an excellent technique for the evaluation of hydrolytic degradation products of the conjugates and for monitoring the release of lipoic acid. The results obtained contribute significantly to the characterization of biocompatible LA-OHB conjugates with potential applications in cosmetology.

Many changes related to aging at the cellular level may be due to the physiological condition of mitochondria. One of the most common types of damage of mtDNA is the so-called "common deletion" referring to a deletion of 4977 base pairs. In the skin cells this phenomenon probably is caused by oxidative damage of mtDNA induced by UV. The present study was aimed at evaluating the effect of the antioxidant L-ergothioneine on UV-induced damage in skin cells. The effect of L-ergothioneine on the reduced glutathione level was studied. The presence of the "common deletion" in human fibroblasts irradiated with UVA and treated with L-ergothioneine was evaluated by a polymerase chain reaction. We have demonstrated that L-ergothioneine enhanced the level of reduced glutathione and protected cells from the induction of a photoaging-associated mtDNA "common deletion". In view of our results, L-ergothioneine could be an effective skin care and anti-photoaging ingredient.

5% vitamin C concentrate is effective in treating capillary and photograph-aging skin. It decreases erythema and telangiectasias as well as triggers the shallowing of skin wrinkles.

Superficial peels, such as 70% GA and 15% TCA, proved to be an effective treatment modality for photodamaged facial skin. Both acids contribute to improvement of the photodamaged skin's parameters. Glycolic acid increases skin's hydration faster.