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Preparation of membrane using crosslinking reaction between chitosan and citric acid showed that functional

The influence of cross-linking and membrane hydrophilicity on the transport rate had been studied using a membrane prepared from a mixture of chitosan/PVA cross-linked citric acid (PVA.cl.CA) for creatinine and urea transport. The optimum mole ratio of PVA:citric acid as well as the best composition of chitosan:PVA.cl.CA were determined using creatinine transport study. Using the optimum compositions, further study was done using different thickness of the membrane in transporting creatinine, urea and a mixture of 3 species (creatinine, urea and vitamin B 12

Abstract-A series of membranes are prepared by solvent drying method, which were composed of N-carboxymehtyl chitosan blended with poly(vinyl alcohol) [N-CMC/PVA]. The N-CMC/PVA membranes showed improved strength properties and permeability for low-molecular weight compounds. This novel membranes exhibited good permeability properties for small molecules also indicated a decrease in protein adsorption on the surface of membrane. The structure and the morphology of the resulting membranes were characterized by FTIR. NMR, elementary analysis and scanning electron microscopy (SEM).