The genus Achillea L. (Asteraceae) is represented by about 115 species found in the northern hemisphere, mostly in Europe and Asia and commonly known as yarrows 1-3. It has been represented in Iran by nineteen species including seven endemics, among this genus, Achillea santolina L. (it has been known as Bomadaran in Iran) is represented in Iran 4. The Achillea L. species belong to the oldest medicinal plants that are used both for pharmaceutical purposes and in folk medicine. These plants contain a complex of different pharmacological compounds, for example, terpenes, flavonoids, alkaloids, bitters, tannins, lignans 5. Achillea species are diuretic, emmenagog agents, wound healing, for curing stomachache, diarrhea and antichloristic, antispasmodic, antiseptic and infection preventing properties and have been used to reduce sweating and to stop bleeding, amarum, stomachicum, cholagolum and carminativum, too 3,6-13. The Achillea genus has a wide distributional range 14 and the differences in oil composition may be affected by different environmental factors, plant genetic type, seasonality and developmental stage, because of a chemically polymorphic and perennial 15. Terpenoids (1,8-cineole, camphor, borneol, pinenes, artemisia ketone, santolina alcohol, farnesane, caryophyllene