AIM:To investigate risk factors associated with Barrett's oesophagus and oesophageal adenocarcinoma. METHODS:This all-Ireland population-based casecontrol study recruited 224 Barrett's oesophagus patients, 227 oesophageal adenocarcinoma patients and 260 controls. All participants underwent a structured interview with information obtained about potential lifestyle and environmental risk factors. RESULTS: CONCLUSION:A high body mass index, a diet low in fruit and cigarette smoking may be involved in the progression from Barrett's oesophagus to oesophageal adenocarcinoma.

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