Skin of an average adult body covers a surface of approximately 2 m2 and receives about one-third of the blood circulating through the body. The transdermal route of administration cannot be employed for a large number of drugs. The rationality of drug selection based on pharmacokinetic parameters and physicochemical properties of the drug are the important factors to be considered for deciding its suitability of drug for delivery by transdermal route.

Under five year olds are often referred to as youngsters under the age of five. Children under the age of five make up 22% of the general population. In comparison to all deaths, the mortality rate for children under the age of five is significant. The danger of numerous health issues is higher in this age range. One of the most significant health issues is home accidents among children under the age of five. Accidents were an unforeseen and unwelcome event, especially when they caused harm or damage. According to the WHO, unintentional accidents are the main cause of death for kids under the age of five. Unintentional injuries include those caused by mishaps including falls, burns, poisoning, drowning, and aspirating foreign objects. This raises concerns about the morbidity and mortality of youngsters. Considering that women are the children's main caregivers. Understanding a mother's beliefs, attitudes, and practices regarding kid safety from accidents at home is essential. According to research, mothers' ignorance of the factors that contribute to home accidents increases their frequency. Investigators noted that preventing home accidents in children under the age of five by educating the mother on the safety measures the investigator had in place to prevent mishaps at home, according to a STP.