The reaction of 2-cyclohexenone, 3-penten-2-one, and 1,3-dipheny 1-2-propen-1 -one with a series of Grignard reagents has been studied in the presence of (-)-sparteine (4) and other additives. The resulting conjugate addition products possess an optical purity of 3-6% and represent the first examples of asymmetric 1,4 addition of achiral organometallic reagents to pro chiral ,ß-unsaturated ketones. Subsequent reactions of enolate anions
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