Abstract.Background: Trimethylamine N-oxide (TMAO) has attracted interest as circulating levels have

Apical sodium-bile acid transporter BCRP Breast Cancer Resistance Protein BLQ Below limit of quantitation CYP2C19 Cytochrome P450 Family 2 Subfamily C Member 19 CYP3A4 Cytochrome P450 Family 3 Subfamily A Member 4 CYP3A5 Cytochrome P450 Family 3 Subfamily A Member 5 DDA Data-dependent acquisition DME Drug metabolizing enzymes DT Drug transporter DTT Dithiothreitol EDTA Ethylenediaminetetraacetic acid ESI Electrospray ionization FA Formic acid FDR False discovery rate IAA Iodoacetamide IHC Immunohistochemistry LC-MS/MS Liquid chromatography with tandem mass spectrometry LLOQ Lower limit of quantitation MCT1 Monocarboxylate transporter 1 MDR1 Multidrug resistance protein 1 or P-glycoprotein MRM Multiple Reaction Monitoring mRNA Messenger RNA MRP2 Multidrug resistance-associated protein 2