A specific gravity, column gradient method was coupled with a tissue punch technique to measure regional edema in the traumatized spinal cord of the cat at 1 and 2 hours after a 500-g/cm impact injury. A significant increase in water content was observed at the injury site in the posterior, anterior, and lateral white columns by 1 hour after injury and extended 2 mm above and below the site by 2 hours after injury.
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