Background: Diabetic foot ulcers (DFU) is one of the major health care problems. Diabetic foot ulcers are a combination of vascular and non-vascular disorders. Vascular disorders that occur in the form of diabetic angiopathy which can be in the form of macro angiopathy if the condition occurs in large blood vessels, and micro angiopathy if it occurs in arterioles and capillaries. Revascularization can be done minimally invasive and has become the gold standard in the management of chronic limb ischemic (CLI). WHO recommends Perfusion, Extent / Size, Depth / Tissue Loss, Infection, Sensation (PEDIS) classification to diagnose and to determine the management of diabetic foot. We conduct a study to find out whether there are improvements in the PEDIS score of diabetic foot ulcer patients post angioplasty Methods: This study was designed in the form of a quasi-experiment, in which measurements before and after treatment were carried out on patients with diabetic foot ulcers (DFU) who underwent revascularization angioplasty without any measurement for control patients. From November 2019 to September 2020, there were 48 cases of diabetic foot ulcer with peripheral artery disease (PAD) who underwent angioplasty. Before the procedure, a clinical evaluation and calculation of the PEDIS score were carried out then angioplasty was performed, after the procedure the PEDIS score was calculated and evaluated in the first, second and third weeks. Results: The PEDIS scores of the patients prior to angioplasty had a median score of 8 (IQR 7; 9). Post-procedure the median quantity fell to 6 on both the immediate post angioplasty and two weeks afterward measurement with the width of the IQR narrowing slightly at the last measurement. The male patients’ PEDIS scores did not differ relatively from those of the female patients at the three measurement times, and their scores were almost identical to the scores for the patients as a whole. Conclusion: The results of this study indicate that there is an improvement in the PEDIS score in diabetic foot ulcer patients after revascularization angioplasty.

Background: Continuous pandemic caused by coronavirus disease (COVID-19) have been associated with high morbidity and mortality. COVID-19 has been linked to a hypercoagulable state that causes cerebrovascular complications. The most common cerebrovascular complication is ischemic stroke.Case Presentations: We report six cases of ischemic stroke with COVID-19, age 51-81 years old, consists of four males and two females. The main risk factors are hypertension and diabetes mellitus. Brain CT scan showed large vessel ischemic stroke in four patients. The patients were treated with Low Molecular Weighted Heparin followed by dual antiplatelet (aspirin and clopidogrel). The outcome was good recovery with minimal sequelae in four patients and death in two patients.Conclusion: Most of the stroke type in COVID-19 is large vessel disease, with main risk factors of hypertension and diabetes mellitus. Treatment with low molecular weight heparin (LMWH) followed by dual antiplatelet showed promising clinical improvement.