Severe stress and depression are common phenomena among mothers of children diagnosed with autism. As a consequence, adequate support becomes necessary in ensuring balanced mental health. Furthermore, religiosity and resilience are key factors influencing psychological well-being development, particularly for mothers, related to self-acceptance, personal development, life goals, understanding of the environment, independence, and positive relationships. Therefore, the objective of this research was to examine the theoretical model of religiosity's effect on psychological well-being with resilience as a mediator for mothers with autistic children in Jakarta, Bogor, Depok, Tangerang, and Bekasi. The purposive sampling technique was applied to 184 respondents with a psychological scale. Also, structural equation modeling (SEM) was employed to assess relevant data, using analysis of moment structure (AMOS v.24). The results were reported to successfully and empirically matched the study objectives. These observations showed mothers in this circumstance were expected to intensely develop resilience by religiosity commitment, and therefore, instigating a very significant psychological well-being.   Received: 19 July 2021 / Accepted: 13 September 2021 / Published: 5 November 2021

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