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As the number of developed sensors is growing, new Internet of Things applications are being developed. Healthcare applications offer a perfect domain for Internet of Things since they respond to the challenge of the ageing population while offering safe and quality care in the home. We present in this paper a new Internet Of Things architecture for IoT healthcare applications. The architecture focuses mainly on the principles of weak coupling and of semantic data exchange. We present a software architecture based on a message oriented middleware driven by semantic OWL messages.