Herpes simplex is a highly prevalent, self limiting viral infection. Complications, drug resistance and side-effects of anti-viral drugs make treatment of herpes simplex challenging. Herbal/Ayurvedic medicines have shown potential in herpes simplex management. We conducted a survey to know the patient reported outcomes of patented Ayurvedic formulation Hyperisince ® . 122 herpes simplex infected patients who were treated with Hyperisince ® were mailed a questionnaire containing 20 questions. The questions collected demographic information, disease information and patient feedback on Hyperisince ® . A total of 101 responses were eligible for evaluation. HSV-1 was present in 31 patients, 48 had HSV-2 and 17 were infected with both the types. Eighty eight (87.13%) were previously treated with other drugs and acyclovir was the most common previous treatment. Symptom relief was reported by 76% of patients. Duration of herpes and nerve pain decreased considerably following Hyperisince ® treatment. There was decrease in frequency of symptoms. The efficacy of Hyperisince ® was more pronounced when it was used for >4 months. Twenty one patients rated Hyperisince ® 10 out of maximum rating of 10 and 58 participants rated it ≥5. Hyperisince ® was effective in relieving symptoms, nerve pain, and improving overall well being. Hyperisince ® also reduced the likelihood of having another herpes outbreak, especially when taken for 4 months or more. Most patients rated efficacy as ≥5 in the scale of 10. Efficacy of Hyperisince ® was more pronounced when used for >4 months. Further clinical trials can confirm our findings.

Background: Trigeminal neuralgia (TN) is a chronic disorder, characterized by unbearable, sudden facial pain, often leads people to suicide. Thus TN is referred to as suicide disease. Aim: The ability of four formulations based on natural medicine, homeopathic, dietary supplements and ayurvedic herbs in different combinations to reduce the complications of TN was investigated with comparative evaluation. Materials & Methods: The study was performed through survey. Questionnaire related to demographic and illness information with TN patient's feedback on the formulations after use, was prepared and randomly sent to the patients, who have received the treatment at the clinic. The responses were collected electronically and detailed statistical analysis was carried out to evaluate the outcome of the treatment. Results: Combinations of all four Biogetica® formulations showed more potential in reducing the disease complications. The treatment with these formulations also displayed improvement in the patient's ability to perform physical activities. Furthermore, no side effects were observed for these formulations after treatment. The combination of 4 biogetica formulas improved the health rate of 68%TN patients. Such results have not been seen in any Drug treatment or gamma knife Surgery. Maximum number of patients ( 26) got the positive result in about 15 to 45 days. But, interestingly, 21 patients got their pain relieved within 15 days of time. Conclusion: The combination of natural medicine, homeopathic, dietary supplements and ayurvedic herbs are effective in alleviating the complications of TN without any adverse effects. Therefore, Biogetica® formulations can be used safely in the treatment of TN.

No abstract